DeepUbi: a deep learning framework for prediction of ubiquitination sites in proteins
DeepUbi：蛋白質泛素化位點預測的深層學習框架 背景 泛素泛素化是指泛素蛋白與賴氨酸(K)的靶蛋白結合，是真核生物中信號轉導、細胞分裂和免疫反應等多種細胞功能的重要調節因子。實驗和臨牀研究表明泛素化在多種人類疾病中起着關鍵作用，蛋白質組學的最新進展引起了人們對泛素化位點識別的興趣。然而，目前大多數預測目標位置的計算工具都是基於小規模數據和淺層機器學習算法。 結果 隨着更多實驗驗證泛素化位點的出
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