<Warped linear mixed models for the genetic analysis of transformed phenotypes>是篇講對數據正態化的新方法的文章,新方法將就叫作彎曲混合線性模型.地址:http://www.nature.com/ncomms/2014/140919/ncomms5890/full/ncomms5890.html.html
文章最後給出了一個python模塊,地址https://github.com/pmbio/warpedLMM. python
可以使用下面命令安裝.git
sudo pip install warpedlmm
惋惜安裝好以後,問題不斷.
github
1.模型依賴GPy模型,不斷提示UserWarning: warning: caught this exception:'module' object has no attribute '_dotblas',目前沒有解決,鑑於只是警告,暫時忽略.shell
2.warpedlmm.py文件18和19行載入語句錯誤,this
import transformations from warping_functions import TanhWarpingFunction_d
應爲:
spa
import util.transformations as transformations from util.warping_functions import TanhWarpingFunction_d
3.模型說明文件中依賴庫有'scipy>=0.13', 'numpy>=1.8', 'matplotlib>=1.2', 'nose', 'fastlmm',可是fastlmm模型依賴sklearn,故要手動安裝code
pip install -U scikit-leran